Eric Dane, the actor known for his roles in "Grey's Anatomy" and "Euphoria," has died at the age of 53. His family confirmed his passing on Thursday, stating that he died from amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease. Dane publicly shared his ALS diagnosis less than a year ago.

A Public Figure for ALS Awareness
Following his diagnosis, Dane became an advocate for ALS awareness. He spoke at a news conference in Washington about issues related to health insurance prior authorization. In recognition of his efforts, the ALS Network named him "advocate of the year" in September, honoring his dedication to raising awareness and support for those affected by the disease. He also expressed gratitude for the "outpouring of love and support" he received from fans.

Career and Personal Life
Dane was a prolific actor with a career spanning from the early 1990s. His most recognized roles include:
Read More: Actor Eric Dane Dies on February 19 2026 at Age 53 from ALS Disease

Dr. Mark Sloan (aka "McSteamy") on the ABC medical drama "Grey's Anatomy," a role he played from 2006 to 2012 and reprised in 2021.
Cal Jacobs on the HBO teen drama "Euphoria."
He also appeared in other television shows like "Charmed" and "The Last Ship," and in films such as "X-Men: Last Stand" and "Burlesque."

Dane's representatives announced his death, with his family requesting privacy during this time. His father died by suicide when Dane was seven years old. He is survived by his two children with ex-wife Rebecca Gayheart.
Understanding ALS
ALS is a progressive disease that affects nerve cells in the brain and spinal cord. It gradually impairs the ability to walk, talk, speak, and breathe. The Mayo Clinic notes that ALS typically leads to muscle control loss, and most patients die within three to five years of diagnosis. The disease affects approximately 30,000 people in the United States.
Eric Dane, known for "Grey's Anatomy" and "Euphoria," has died at 53.
His death was attributed to ALS, a condition he publicly revealed less than a year prior.
Dane actively became an advocate for ALS awareness following his diagnosis.
Sources:
CBS News: https://www.cbsnews.com/news/eric-dane-greys-anatomy-euphoria-dies-at-53/
The Guardian: https://www.theguardian.com/tv-and-radio/2026/feb/20/eric-dane-dies-aged-53-death-greys-anatomy-euphoria-star
AP News: https://apnews.com/article/eric-dane-dead-a2eaf3916d047c038ac1121af9a99f17
Rolling Stone: https://www.rollingstone.com/tv-movies/tv-movie-news/eric-dane-euphoria-greys-anatomy-dead-obituary-1235519747/
Today: https://www.today.com/popculture/news/eric-dane-dies-53-als-rcna242642
NBC New York: https://www.nbcnewyork.com/entertainment/entertainment-news/eric-dane-obit-greys-anatomy-euphoria-als/6465488/