Actor Eric Dane, known for his roles in "Grey's Anatomy" and "Euphoria," has died at the age of 53. His family confirmed his passing on Thursday, stating that his death was due to complications from amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease. Dane had publicly shared his diagnosis less than a year prior to his death, subsequently becoming an advocate for ALS awareness and research.
Background
Eric Dane's career spanned decades, with notable roles in television and film. He gained widespread recognition for his portrayal of Dr. Mark Sloan, "McSteamy," on the popular ABC medical drama "Grey's Anatomy" from 2006 to 2012, and later reprised the role. He also played Cal Jacobs in the HBO series "Euphoria" and had earlier roles in "Charmed," "The Last Ship," and films like "X-Men: Last Stand" and "Burlesque."

Dane was married to actress Rebecca Gayheart, with whom he had two daughters. He publicly announced his ALS diagnosis in April 2025. Following his diagnosis, Dane became actively involved in raising awareness for ALS, speaking at events and advocating for improved health insurance policies for those with neurodegenerative diseases. He was honored with the ALS Network's advocate of the year award in September 2025.

Evidence of Death and Cause
Multiple reputable news outlets, including CBS News, BBC News, ABC News, Associated Press, CNN, Rolling Stone, The Hollywood Reporter, and Variety, reported Eric Dane's death on Thursday, February 19, 2026. His representatives and family confirmed the news.

Cause of Death: Representatives stated Dane died from amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease.
Timing of Announcement: The news of his death arrived approximately 10 months after he publicly shared his ALS diagnosis.
Eric Dane's Public Advocacy for ALS
Following his diagnosis, Eric Dane dedicated a significant portion of his time to advocating for ALS awareness and research. His efforts included:

Speaking Engagements: He spoke at a news conference in Washington D.C. concerning health insurance prior authorization policies for ALS patients.
Recognition: In September 2025, the ALS Network recognized his commitment by naming him their advocate of the year.
Personal Mission: Dane expressed a desire to share his journey openly, stating he felt it was "imperative" and that his life was no longer solely about himself. He viewed his advocacy as a way to help others and to model resilience for his daughters.
Dane's Health Status Prior to Death
Dane was candid about the progression of his ALS. In a June 2025 interview with ABC News, he described the physical impact of the disease:
"My left side is functioning; my right side has completely stopped working."
He indicated a rapid loss of voluntary function in his left arm, expressing concern about losing the use of his left hand within "a couple, few more months."
Despite the progression of his illness, Dane expressed a determination to continue his work. He mentioned planning to keep acting and that he felt a "fight to the last breath" was necessary. His final acting role was in October 2025, where he played a firefighter with ALS in NBC's "Brilliant Minds."
Public Reaction and Family's Request
The news of Eric Dane's death has been met with widespread coverage from major news outlets. His family has requested privacy during this difficult time as they "navigate this impossible time."
Sources
CBS News: https://www.cbsnews.com/news/eric-dane-greys-anatomy-euphoria-dies-at-53/
ABC News: https://abcnews.com/GMA/Culture/greys-anatomy-star-eric-dane-dies-53-after/story?id=124500080
ABC Australia: https://www.abc.net.au/news/2026-02-20/eric-dane-star-of-greys-anatomy-and-euphoria-dies/106188556
Associated Press: https://apnews.com/article/eric-dane-dead-a2eaf3916d047c038ac1121af9a99f17
CNN: https://edition.cnn.com/2026/02/19/entertainment/eric-dane-death
Rolling Stone: https://www.rollingstone.com/tv-movies/tv-movie-news/eric-dane-euphoria-greys-anatomy-dead-obituary-1235519747/
The Hollywood Reporter: https://www.hollywoodreporter.com/tv/tv-news/eric-dane-dead-greys-anatomy-mcsteamy-1236510346/
Variety: https://variety.com/2026/tv/news/eric-dane-dead-mcsteamy-greys-anatomy-euphoria-1236667968/