The FA Cup quarter-finals are set to unfold this weekend, featuring a marquee clash between Manchester City and Liverpool as the centerpiece of the round. All four matches are slated to be broadcast on ESPN networks, with other ties including Chelsea facing lower-league opposition in Port Vale, West Ham United taking on Leeds United in a battle for Premier League survival, and Southampton meeting Arsenal.

CITY VS. LIVERPOOL: A HIGH-STAKES ENCOUNTER
The highly anticipated match between Manchester City and Liverpool will take place at the Etihad Stadium. =This fixture represents the seventh FA Cup tie between the two clubs,= with historical data showing Manchester City with 62 wins and Liverpool with 110 victories in their encounters. Odds suggest Manchester City is favored to advance, with some outlets offering 2/5 for their qualification versus 15/8 for Liverpool.

Team News: Manchester City is facing potential absences due to injuries, with Ruben Dias, John Stones, and Josko Gvardiol all being assessed.
Recent Form: Manchester City secured a victory in the Carabao Cup final against Arsenal prior to this fixture. Liverpool, conversely, has shown inconsistent form, including a recent Premier League loss to Brighton.
Goalmouth Action: Many predict a high-scoring affair, with expectations of both teams finding the net and the total score exceeding 2.5 goals. =Eighteen of the last 19 meetings between these two clubs have seen two or more goals scored.=
OTHER FA CUP QUARTER-FINAL PREDICTIONS
CHELSEA VS. PORT VALE
Chelsea is expected to advance against League One side Port Vale, though the latter has demonstrated a capability for upsets in cup competitions this season, having won seven games in the FA and League Cups combined.
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WEST HAM VS. LEEDS UNITED
This encounter pits two teams primarily focused on Premier League survival against each other. The match is anticipated to be a closely fought contest, with both sides potentially prioritizing their league status. =Leeds United has a 1-1 draw prediction against West Ham.=
SOUTHAMPTON VS. ARSENAL
Southampton, in strong home form with six wins in their last seven, faces Arsenal. While Arsenal is expected by some to progress, they are anticipated to face a difficult challenge from a Southampton side that has shown significant improvement. =A prediction of Southampton 1-2 Arsenal is noted.=
BACKGROUND CONTEXT
The FA Cup, referred to as soccer's oldest competition, sees its quarter-final stage featuring a mix of Premier League, Championship, and League One clubs. For Liverpool, the FA Cup, alongside the Champions League, represents their remaining opportunities for silverware this season. =Mohamed Salah's final games for Liverpool= are approaching, with this potentially being his last encounter against Manchester City as a Liverpool player.
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