The entertainment world is acknowledging the passing of actor Eric Dane, 53, known for his roles in "Grey's Anatomy" and "Euphoria." His family confirmed his death on Thursday, following a public announcement of his amyotrophic lateral sclerosis (ALS) diagnosis less than a year prior. Dane had become an advocate for ALS awareness, speaking on health insurance and research.
Timeline of Events
Eric Dane's public journey with ALS, from diagnosis to his passing, spanned approximately one year.

April 2025: Dane publicly announced his diagnosis with ALS. He expressed a desire to continue acting and share his experience.
June 2025: Dane spoke with ABC's Diane Sawyer, detailing the progression of the disease, noting that the right side of his body had stopped working and he was losing function in his left arm.
September 2025: The ALS Network recognized Dane with their advocate of the year award for his efforts in raising awareness and support.
December 2025: Dane participated in a virtual panel, stating his intention to continue sharing his journey.
February 2026 (specific date not provided by all sources, but within hours of publication): Eric Dane passed away at the age of 53.
Career Highlights
Dane achieved widespread recognition for his role as Dr. Mark Sloan, known as "McSteamy," on the ABC medical drama "Grey's Anatomy." He portrayed the character from 2006 to 2012 and reprised the role in 2021. His other notable television work includes roles in "Euphoria" and "Charmed." He also appeared in films such as "X-Men: Last Stand" and "Burlesque."
Personal Background
Born Eric William Dane, he had a career dating back to the early 1990s. Reports indicate his father died by suicide when Dane was seven years old, leaving his mother to raise him and his sibling. Dane had spoken about personal struggles, including depression and previous rehab stays in his younger years.
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Evidence of Passing and Diagnosis
Multiple credible news outlets have reported Eric Dane's death, citing his family's announcement. The cause of death has been consistently identified as amyotrophic lateral sclerosis (ALS).
Family Confirmation: "Eric Dane, 'Grey's Anatomy' star, dies at 53," his family announced Thursday. (CBS News)
Cause of Death: "His representatives said Dane died from amyotrophic lateral sclerosis (ALS), a neurodegenerative disorder known also as Lou Gehrig's disease, less than a year after he announced his diagnosis." (CBC News, Associated Press, ABC News, Los Angeles Times, ABC Australia)
Diagnosis Timing: Reports consistently note the diagnosis was announced "less than a year" or "nearly a year" before his death. (CBC News, Associated Press, Today, ABC Australia)
Dane's Advocacy for ALS Awareness
Following his diagnosis, Eric Dane actively engaged in raising awareness and advocating for those affected by ALS.

Public Speaking: Dane spoke at a news conference in Washington concerning health insurance prior authorization. (CBS News, Associated Press, ABC Australia)
Award Recognition: In September 2025, the ALS Network honored Dane as their advocate of the year. (CBS News, Associated Press)
Personal Motivation: Dane stated, "I don't feel like my life is about me anymore," indicating a shift in focus towards his advocacy efforts. (CBS News, CNN) He also expressed a hope to "model" a forward-moving attitude for his daughters. (ABC News)
The Progression of ALS
Sources describe ALS as a progressive neurodegenerative disorder that impacts nerve cells responsible for muscle control.
Impact on Function: ALS "gradually destroys the nerve cells and connections needed to walk, talk, speak and breathe." (CBC News, Associated Press)
Personal Account: Dane himself described the physical effects: "My left side is functioning; my right side has completely stopped working," and noted the rapid loss of voluntary function in his left arm. (ABC News)
Prognosis: "Most patients die within three to five years of a diagnosis." (CBC News)
Professional Impact and Future Roles
Dane's acting career spanned several decades, with significant roles in popular television series and films.

"Grey's Anatomy": His breakout role as Dr. Mark Sloan began in 2006 and continued for eight seasons. (CBS News, ABC News, Associated Press, CNN, Los Angeles Times, Cinemablend)
"Euphoria": Dane played Cal Jacobs in the series, and was listed as set to appear in the third season. (CNN, Los Angeles Times, Cinemablend)
Other Credits: His filmography includes "X-Men: The Last Stand," "Marley & Me," and "Burlesque." (CBS News, CNN)
Expert and Representative Statements
While no direct quotes from medical experts are provided regarding Dane's specific case, his representatives and family have released statements.
"He will be deeply missed, and lovingly remembered always." (CBC News)
"The family has asked for privacy as they navigate this impossible time." (CBS News)
Conclusion and Implications
The death of Eric Dane at 53 brings attention to ALS, a serious neurodegenerative disease. His transition from actor to advocate highlights the personal impact of such diagnoses and underscores the ongoing need for research and support for affected individuals and their families. His public advocacy may encourage further awareness and potentially influence policy regarding health insurance and research funding for neurodegenerative diseases. The family's request for privacy is a signal of their need for space during a period of grief.
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Sources
CBS News: https://www.cbsnews.com/news/eric-dane-greys-anatomy-euphoria-dies-at-53/ - Reports on Dane's death, advocacy, and career.
CBC News: https://www.cbc.ca/news/entertainment/eric-dane-greys-anatomy-als-dead-9.7098653 - Details Dane's death from ALS and explains the disease.
CNN: https://edition.cnn.com/2026/02/19/entertainment/eric-dane-death - Covers Dane's advocacy efforts and career roles.
ABC News: https://abcnews.go.com/GMA/Culture/greys-anatomy-star-eric-dane-dies-53-after/story?id=124500080 - Reports on Dane's passing, diagnosis, and personal account of the disease's progression.
Associated Press: https://apnews.com/article/eric-dane-dead-a2eaf3916d047c038ac1121af9a99f17 - Confirms Dane's death from ALS and highlights his advocacy work.
Los Angeles Times: https://www.latimes.com/entertainment-arts/story/2026-02-19/eric-dane-dead-greys-anatomy-als - Details Dane's death from ALS and mentions his career.
Today: https://www.today.com/popculture/news/eric-dane-dies-53-als-rcna242642 - Confirms Dane's death and discusses ALS as a disease.
ABC Australia: https://www.abc.net.au/news/2026-02-20/eric-dane-star-of-greys-anatomy-and-euphoria-dies/106188556 - Reports on Dane's death from ALS and his advocacy.
Cinemablend: https://www.cinemablend.com/television/greys-anatomy-and-euphoria-star-eric-dane-is-dead-at-53 - Notes Dane's death after battling ALS and mentions his popular roles.